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Cialis Black

Cialis Black is the brand name for the drug cialis (tadalafil). It is the generic name for the drug tadalafil. This medication is the most common use of this drug. Cialis is used to treat erectile dysfunction (ED) in men. ED can be caused by a number of factors, such as heart disease, diabetes, high blood pressure, high cholesterol, or a stroke. Cialis works by increasing blood flow to the penis, which helps men get and maintain an erection. Cialis is available as a generic medication. Cialis Black is available in the following strengths: 5 milligrams (mg) (4 mg) and 10 mg, 5 mg, 10 mg, 20 mg, and 40 mg. The recommended starting dose is 10 mg, which should be taken on an empty stomach. The maximum recommended dose is 40 mg, and should not be taken more than once per day. Taking the drug more than once per day may increase the risk of side effects, such as dizziness, vision changes, and hearing loss. If you are taking Cialis Black, do not take it more than once a day. Do not take Cialis Black if you: are allergic to any ingredients in Cialis Black or any of its other ingredients. It is not known if Cialis Black is effective for all men. Cialis Black is not recommended for women and children. If you are pregnant or breastfeeding, consult your healthcare provider before taking Cialis Black. Before taking Cialis Black, tell your doctor if you have liver problems, heart problems, or a history of diabetes. Cialis Black may affect the way other medicines work or cause side effects. Cialis Black should not be used in the treatment of erectile dysfunction. Do not use Cialis Black if you are taking nitrates (medicines used to treat angina, chest pain, or heart problems). Nitrates are usually not used long-term, and Cialis Black may cause a drop in blood pressure that could lead to heart attacks, strokes, or even heart failure. The drug Cialis Black may cause dizziness in some individuals. If you experience any of these, do not drive or operate heavy machinery until you know how you react to the drug. Cialis Black is not recommended for use in children under 8 years of age, as there is a risk of side effects in these young people. Cialis Black should not be used by women or children. It is not known if Cialis Black is safe or effective for use by women or children. Cialis Black is not recommended for use by women or children. If you are taking Cialis Black, tell your doctor about all your other medicines and herbal products. Do not take Cialis Black if you are taking any other medications, including any vitamins and supplements. Do not use Cialis Black if you are allergic to any ingredients in Cialis Black or any of its ingredients. Do not take Cialis Black if you are taking nitrates (medicines used to treat angina, chest pain, or heart problems).

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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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C. Preventative Measures:

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Other Hypertens:

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Nitrates (e.g., nitroglycerin):Cialis can cause a severe drop in blood pressure that can lead to symptoms like dizziness, lightheadedness, or fainting. It is contraindicated to use Cialis with nitrates or recreational "poppers" (e.g., amyl nitrites).

4.Alpha-blockers (e.g. prazosin, terazosin, tamsulosin):Cialis can enhance the blood pressure-lowering effects of the medications.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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As with most medications, Cialis can cause potentially serious adverse reactions that need medical attention.

Active ingredient

Tadalafil

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Active ingredient: Tadalafil

Mode of action

Inhibits protein synthesis by binding to and blocking the enzyme phosphodiesterase type 5 (PDE5). This enzyme is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP leads to smooth muscle relaxation in the penis. As a result, cGMP is broken down, causing increased blood flow and erectile function.